A New Neurosis. (Thomsen's Disease)
نویسنده
چکیده
symptom spasmodic and tonic cramp in muscles, occurring suddenly and irregularly on attempting voluntary movement. In January, 1883, MM. Ballet and Marie published a case of this disease (.Archives de Ndurologie), naming it "muscular spasm at the commencement of voluntary movements." In March, 1883, Westphal brought two cases of the disease before the Society of Medicine of Berlin, and quoted six other cases which
منابع مشابه
Fluctuating clinical myotonia and weakness from Thomsen's disease occurring only during pregnancies.
Advances in molecular genetics are allowing better phenotype to genotype correlation of the non-dystrophic myotonic disorders. We report a 32-year-old woman, who first noted myotonia that was associated with weakness during her first pregnancy. The work-up disclosed that she had Thomsen's disease which is not known to be associated with weakness. In addition, her myotonia was of the fluctuating...
متن کاملCo-occurrence of multiple sclerosis and Thomsen's myotonia: a report of two cases.
Multiple sclerosis (MS) is a common demyelinating disease of the central nervous system in which an abnormal immune system response results in damage to the myelin sheaths surrounding nerves. The etiology of MS remains elusive, although it has been suggested to be influenced by both genetic and environmental factors. Here, we report two exceptional cases of patients affected by both MS and Thom...
متن کاملMyotonia levior is a chloride channel disorder.
The group of dominant non-dystrophic myotonias, comprising disorders characterized by clinically similar forms of myogenic muscle stiffness, is genetically inhomogeneous. Dominant myotonia congenita (Thomsen's disease) is linked to CLCN1, the gene encoding the major muscle chloride channel, localized on chromosome 7q35. In contrast, dominant myotonias sensitive to potassium are caused by point ...
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